重组Human GDF15/MIC-1蛋白,His Tag 人生长分化因子-15(GDF15/MIC-1蛋白)（92008ES）

生长分化因子 15 (GDF15)，也称为 NSAID 激活基因-1 (NAG-1)，与许多生物过程和疾病有关，包括癌症和肥胖症。GDF15 前体为pro-GDF15，二聚化，裂解后作为成熟二聚体 GDF15 分泌到循环中。

高纯度、高活性、低内毒素、高批间一致性

                                       SDS-PAGE

Human GDF15 on Bis-Tris PAGE under reduced (R) condition and Non reduced (N) condition. The purity is greater than 95%.

                                          Blocking Data

Serial dilutions of Anti-GDF15 Antibody were added into Human GDF15, His Tag : Biotinylated Human GFRAL, His Tag binding reactioins. The half maximal inhibitiory concentration (IC50) is 40.8 ng/ml.

                                                 ELISA Data

Immobilized Human GDF15, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Human GFRAL, hFc Tag with the EC50 of 13.1 ng/ml determined by ELISA.

                                           SPR Data

Human GFRAL, hFc Tag captured on CM5 Chip via Protein A can bind Human GDF15, His Tag with an affinity constant of 0.014 nM as determined in SPR assay.

-25 ~ -15℃保存，收到货之后有效期1年。
复溶后， -85 ~ -65℃保存，3个月有效期。