产品简介

DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head-forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play important regulatory roles in the Wnt/β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system.

 

性能参数

Synonyms	Dickkopf-related protein-1, Dickkopf-1, SK
Uniprot No.	O94907
Source	Mouse DKK-1 Protein is expressed from HEK293 without tag. It contains Ser30-His272.
Molecular Weight	The protein has a predicted 26.1 kDa
Purity	> 95% as determined by SDS-PAGE.
Endotoxin	< 1.0 EU per 1μg of the protein by the LAL method.
Formulation	Dissolved in sterile PBS buffer. This solution can be diluted into other aqueous buffers. Centrifuge the vial prior to opening.

 

储存条件

The product should be stored at -85~-65℃ for 1 year from date of receipt.

Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

注意事项

1. Please operate with lab coats and disposable gloves,for your safety.   
2. This product is for research use only.

Ver. CN20240202