p16-INK4A a cell-cycle regulatory protein that Interacts with CDK4 and CDK6, inhibiting their ability to interact with cyclins D. Inhibits the phosphorylation of the retinoblastoma protein by CDK4 or CDK6. Four alternatively spliced isoforms have been reported.
产品性质
别名 |
CDKN2A; CDKN2; MTS1; Cyclin-dependent kinase inhibitor 2A; isoforms 1/2/3; Cyclin-dependent kinase 4 inhibitor A; CDK4I; Multiple tumor suppressor 1; MTS-1; p16-INK4a; p16-INK4; p16INK4A |
SwissProt ID |
P42771 |
基因ID |
1029 |
免疫原 |
Recombinant protein of human CDKN2A/p16INK4a |
缓冲液 |
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
分子量 |
Calculated MW: 17 kDa; Observed MW: 17 kDa |
克隆类型 |
Monoclonal Antibody |
亚型 |
IgG |
宿主 |
Rabbit |
物种反应 |
Human,Mouse |
推荐应用 |
WB,ICC/IF |
纯化方式 |
Affinity Purified |
应用
稀释比 WB: 1/500-1/1000;IF: 1/50-1/200
储存条件
-25~-15℃保存
注意事项
1. 避免反复冻融。
2. 本产品仅作科研用途。
2. 为了您的安全和健康,请穿实验服并佩戴一次性手套操作。
产品数据