Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis . Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling .

稀释比 WB: 1/500-1/1000 IHC: 1/50-1/100

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。