Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity.

推荐稀释比 WB:1/500-1/1000;IF:1/50-1/200;IP:1/20

Immunocytochemistry analysis of Presenilin 1 (green) in SKOV-3 using Presenilin 1 antibody,and DAPI(blue).

Western blot analysis of Presenilin 1/PS1 in mouse colon, mouse gastric lysates using Presenilin 1/PS1 antibody.

Western blot analysis of Presenilin 1/PS1 in Hela, C6, Jurkat lysates using Presenilin 1/PS1 antibody

Store at 4°C short term. Aliquot and store at -49°C long term. Avoid freeze/thaw cycles.