Cofilin Rabbit pAb
产品介绍
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]
产品性质
产品特色
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
应用案例
Western
Western blot analysis of Cofilin in MDA lysates using coflin1/cofilin2 (Ab88) antibody.
Immunofluorescence
Immunofluorescence analysis of Cofilin in Hela using coflin1/cofilin2 (Ab88) antibody.
Immunohistochemistry
Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using coflin1/cofilin2 (Ab88) antibody (left) or the same antibody preincubated with blocking peptide (right).High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
存储条件
-15到-25度
COA
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