产品简介

 

MMAE, or monomethyl auristatin E, is a potent cytotoxic agent commonly used in the development of antibody-drug conjugates (ADCs) for targeted cancer therapy. It is an antimitotic agent which inhibits cell division by blocking the polymerization of tubulin.

 

产品性质

 

来源	Monoclonal anti-MMAE antibody, is produced from a hybridoma which was obtained from a mouse immunized with MMAE.
缓冲液	1×PBS, pH7.4.
克隆类型	Monoclonal Antibody
亚型	IgG1
宿主	Mouse
消光系数	1.4
浓度	1 mg/mL
纯度	＞94% as determined by reduced SDS-PAGE ＞97% as determined by non-reduced SDS-PAGE > 98% as determined by SEC-HPLC
活性	EC50=6.3 ng/mL by ELISA
应用	ELISA

 

储存条件

 

-25~-15℃保存

 

注意事项

 

1. 避免反复冻融。

2. 本产品仅作科研用途。

3. 为了您的安全和健康，请穿实验服并佩戴一次性手套操作。

 

产品数据  

 

SDS-PAGE

 

SEC-HPLC

ELISA Data
 

Ver.CN20240726