产品简介

 

SN38 is the active metabolite of the chemotherapy drug irinotecan (Camptosar). It is  a topoisomerase I inhibitor, prevents the enzyme from properly resealing the DNA strands after they have been unwound, which leads to the accumulation of DNA damage.

 

产品性质

 

来源	Monoclonal anti-SN38 antibody, is produced from a hybridoma which was obtained from a mouse immunized with SN38..
缓冲液	1×PBS, pH7.4.
克隆类型	Monoclonal Antibody
亚型	IgG1
宿主	Mouse
消光系数	1.4
浓度	1 mg/mL
纯度	＞95% as determined by reduced SDS-PAGE ＞99% as determined by non-reduced SDS-PAGE > 99% as determined by SEC-HPLC
活性	EC50=80.5 ng/mL by ELISA
应用	ELISA

 

储存条件

 

-25~-15℃保存

 

注意事项

 

1. 避免反复冻融。

2. 本产品仅作科研用途。

3. 为了您的安全和健康，请穿实验服并佩戴一次性手套操作。

 

产品数据 

 

SDS-PAGE

 

SEC-HPLC

ELISA Data

 

Ver.CN20240726