产品信息
产品名称 |
产品编号 |
规格 |
OTUB1 Rabbit mAb |
31439ES50 |
50 μL |
31439ES60 |
100 μL |
产品简介
Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation. Deubiquitinates estrogen receptor alpha (ESR1). Mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains, but not 'Lys-63'-linked polyubiquitin chains. Not able to cleave di-ubiquitin. Also capable of removing NEDD8 from NEDD8 conjugates, but with a much lower preference compared to 'Lys-48'-linked ubiquitin.
产品性质
别名 |
OTUB1; OTB1; OTU1; HSPC263; Ubiquitin thioesterase OTUB1; |
SwissProt ID |
Q96FW1 |
基因ID |
55611 |
免疫原 |
A synthetic peptide of human OTUB1. |
缓冲液 |
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. |
分子量 |
Calculated MW: 31 kDa; Observed MW: 31 kDa |
克隆类型 |
Monoclonal Antibody |
亚型 |
IgG |
克隆号 |
6I3 |
宿主 |
Rabbit |
物种反应 |
Human, Mouse, Rat |
推荐应用 |
WB, IP |
纯化方式 |
Affinity Purified |
应用
稀释比 WB:1/500-1/1000; IP:1/20
储存条件
-25~-15℃保存
注意事项
1. 避免反复冻融。
2. 本产品仅作科研用途。
3. 为了您的安全和健康,请穿实验服并佩戴一次性手套操作。
产品数据
Western blot
Ver.CN20231229