产品说明书
FAQ
COA
已发表文献
该基因编码一个110-kD的跨膜糖蛋白，在人单核细胞和组织巨噬细胞中高度表达。它是溶酶体/内体相关膜糖蛋白(LAMP)家族的成员。该蛋白主要定位于溶酶体和核内体，一小部分循环到细胞表面。它是一种I型整合膜蛋白，具有高度糖基化的胞外结构域，与组织和器官特异性凝集素或选择素结合。这种蛋白质也是清道夫受体家族的一员。清道夫受体的典型功能是清除细胞碎片，促进吞噬作用，并介导巨噬细胞的招募和激活。选择性剪接导致多个转录本编码不同的异构体。
产品性质
|
别名 |
CD68 antigen, Macrophage antigen CD68 (microsialin), GP110 |
|
SwissProt ID |
P34810 |
|
基因ID |
968 |
|
免疫原 |
Synthetic Peptide of CD68 |
|
缓冲液 |
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
|
分子量 |
Observed MW (kDa):37 |
|
克隆类型 |
Monoclonal Antibody |
|
亚型 |
IgG1 |
|
宿主 |
Mouse |
|
物种反应 |
Human,Mouse |
|
纯化方式 |
Affinity Purified |
|
细胞定位 |
细胞膜，核内体膜，溶酶体膜，单通I型膜蛋白，单通I型膜蛋白 |
|
研究领域 |
免疫学与炎症 |
应用
稀释比IHC: 1/200 ICC: 1/50-200
 |
Immunohistochemical analysis of paraffin-embedded Human Tonsil tissue. 1,CD68 Monoclonal Antibody was diluted at 1:200 (4°C,overnight). 2, Sodium citrate pH 6.0 was used for antibody retrieval (>98°C,20min). 3,Secondary antibody was diluted at 1:200 (room tempeRature, 30min). Negative control was used by secondary antibody only. |
|
|
Immunohistochemical analysis of paraffin-embedded Mouse liver tissue. 1,CD68 Monoclonal Antibody was diluted at 1:200 (4°C,overnight). 2, Sodium citrate pH 6.0 was used for antibody retrieval (>98°C,20min). 3,Secondary antibody was diluted at 1:200(room tempeRature, 30min). Negative control was used by secondary antibody only. |
|
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Immunofluorescence analysis of Human-lung-cancer tissue. 1,CD68 Monoclonal Antibody(6F3)(red) was diluted at 1:200(4°C,overnight). 2, Cy3 labled Secondary antibody was diluted at 1:300(room temperature, 5min). 3, Picture B: DAPI(blue) 1min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B. |
运输与保存方法
冰袋运输。-20℃保存，1年有效期。
注意事项
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3. 本产品仅作科研用途！
HB220607
