PKN1 Rabbit mAb
产品介绍
The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
产品性质
产品特色
推荐稀释比 WB:1/500-1/1000
应用案例
Western blot analysis of PKN in C6 lysates using PKN1 antibody.
存储条件
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
COA
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