Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.

Western

Western blot analysis of Atg16L1 in HeLa lysates using ATG16L1 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。