The protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature.

Western

Western blot analysis of ECHS1 in 293T, MCF-7, PC-3, Human fetal liver, Hela lysates using ECHS1 antibody

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human brain using ECHS1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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