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克隆与点突变

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25.Wang M, Nie Y, Wu X L. Membrane vesicles from a Dietzia bacterium containing multiple cargoes and their roles in iron delivery[J]. Environmental microbiology, 2020.(IF4.93)    


26.Chen B, Chen Z, Wang Y, et al. ORF4 of the temperate archaeal virus SNJ1 governs the lysis-lysogeny switch and superinfection immunity[J]. Journal of Virology, 2020.(IF4.501)  


27.Yan, X., et al., The New Synthetic H2S-Releasing SDSS Protects MC3T3-E1 Osteoblasts against H2O2-Induced Apoptosis by Suppressing Oxidative Stress, Inhibiting MAPKs, and Activating the PI3K/Akt Pathway[J]. Front Pharmacol, 2017. 8: p. 07.(IF4.4)    


28.Zhang S, Zhang Z, Shen Y, et al. SCN9A epileptic encephalopathy mutations display a gain-of-function phenotype and distinct sensitivity to oxcarbazepine[J]. Neuroscience Bulletin, 2020, 36(1): 11-24.(IF4.326)    


29.Liang, W., et al., Anti-Restriction Protein, KlcAHS, Promotes Dissemination of Carbapenem Resistance[J]. Front Cell Infect Microbiol, 2017. 7: p. 150.(IF4.3)    


30.Wang, X., et al., Improved PKS gene expression with strong endogenous promoter resulted in geldanamycin yield increase[J]. Biotechnol J, 2017.(IF4.3)    


31.Wang C, Fu J, Wang M, et al. Bartonella quintana type IV secretion effector BepE‐induced selective autophagy by conjugation with K63 polyubiquitin chain[J]. Cellular microbiology, 2019, 21(4): e12984.(IF4.288)    


32.Wu, R., et al., Direct regulation of the natural competence regulator gene tfoX by cyclic AMP (cAMP) and cAMP receptor protein (CRP) in Vibrios[J]. Sci Rep, 2015. 5: p. 14921.(IF4.25)    


33.Zhang S, Zhang Z, Shen Y, et al. SCN9A epileptic encephalopathy mutations display a gain-of-function phenotype and distinct sensitivity to oxcarbazepine[J]. Neuroscience bulletin, 2019: 1-14.(IF4.246)    


34.Li D, Cheng P, Wang J, et al. IRF6 is directly regulated by ZEB1 and ELF3, and predicts a favorable prognosis in gastric cancer[J]. Frontiers in oncology, 2019, 9: 220.(IF4.137)    


35.Bai Y, Lu J, Cheng Y, et al. NF-кB increases LPS-mediated procalcitonin production in human hepatocytes[J]. Scientific reports, 2018, 8(1): 8913.(IF4.011)    


36.He, D.X., et al., A methylation-based regulatory network for microRNA 320a in chemoresistant breast cancer[J]. Mol Pharmacol, 2014. 86(5): p. 536-47.(IF3.92)   

 

37.Zhu H, Cao Y, Su W, et al. Enterovirus A71 VP1 Variation A289T Decreases the Central Nervous System Infectivity via Attenuation of Interactions between VP1 and Vimentin In Vitro and In Vivo[J]. Viruses, 2019, 11(5): 467.(IF3.811)    


38.Pan Q, Tong Y, Han Y J, et al. Two amino acids missing of MtrA resulted in increased erythromycin level and altered phenotypes in Saccharopolyspora erythraea[J]. Applied microbiology and biotechnology, 2019, 103(11): 4539-4548.(IF3.67) 


39.Yi J, Zhang D, Cheng Y, et al. The impact of Paenibacillus polymyxa HY96-2 luxS on biofilm formation and control of tomato bacterial wilt[J]. Applied microbiology and biotechnology, 2019, 103(23-24): 9643-9657.(IF3.67)    


40.Long L, Sun L, Lin Q, et al. Characterization and functional analysis of two novel thermotolerant α-L-arabinofuranosidases belonging to glycoside hydrolase family 51 from Thielavia terrestris and family 62 from Eupenicillium parvum[J]. Applied microbiology and biotechnology, 2020, 104(20): 8719-8733.(IF3.53)    


41.Zhang L, Jiang Y, Zhu Y, et al. Functional characterization of GI and CO homologs from Eriobotrya deflexa Nakai forma koshunensis[J]. Plant cell reports, 2019, 38(5): 533-543. (IF3.499)    


42.Chen H Y, Gao L T, Yuan J Q, et al. Decrease in SHP-1 Enhances Myometrium Remodeling via FAK Activation Leading to Labor[J]. American Journal of Physiology-Endocrinology and Metabolism, 2020.(IF3.469)    


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44.Xing H, Zou G, Liu C, et al. Improving the thermostability of a GH11 xylanase by directed evolution and rational design guided by B-factor analysis[J]. Enzyme and Microbial Technology, 2020: 109720.(IF3.448)    


45.Wei M, Zhu Z, Wu J, et al. DRAM1 deficiency affects the organization and function of the Golgi apparatus[J]. Cellular signalling, 2019, 63: 109375.(IF3.388)    


46.Deng H, Xu X, Hu L, et al. A janus kinase from Scylla paramamosain activates JAK/STAT signaling pathway to restrain mud crab reovirus[J]. Fish & shellfish immunology, 2019, 90: 275-287.(IF3.298)    


47.Yao M, Dong Y, Wang Y, et al. N6-methyladenosine modifications enhance enterovirus 71 ORF translation through METTL3 cytoplasmic distribution[J]. Biochemical and Biophysical Research Communications, 2020, 527(1): 297-304.(IF2.985)    


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50.Yan L, Liu G, Cao H, et al. Hsa_circ_0035483 sponges hsa-miR-335 to promote the gemcitabine-resistance of human renal cancer cells by autophagy regulation[J]. Biochemical and biophysical research communications, 2019, 519(1): 172-178. (IF2.705)  


51.Li W, Fang J, Shen J, et al. MicroRNA-135a-5p promotes neuronal differentiation of pluripotent embryonal carcinoma cells by repressing Sox6/CD44 pathway[J]. Biochemical and biophysical research communications, 2019, 509(2): 603-610.(IF2.705) 


52.Yang M, Zhu L, Zhu L, et al. Role of a Rare Variant in APC Gene Promoter 1B Region in Classic Familial Adenomatous Polyposis[J]. Digestion, 2020: 1-7.(IF2.692)    


53.Ke Y, Yu D, Zhang F, et al. Recombinant vesicular stomatitis virus expressing the spike protein of genotype 2b porcine epidemic diarrhea virus: A platform for vaccine development against emerging epidemic isolates[J]. Virology, 2019, 533: 77-85.(IF2.657)   

 

54.Xu R, Li D, Peng J, et al. Cloning, expression and antioxidant activity of a novel collagen from Pelodiscus sinensis[J]. World Journal of Microbiology and Biotechnology, 2016, 32(6): 100. (IF2.652)    


55.Li K, Zhao B, Wei D, et al. Long non‐coding RNA ANRIL enhances mitochondrial function of hepatocellular carcinoma by regulating the MiR‐199a‐5p/ARL2 axis[J]. Environmental toxicology, 2019.(IF2.649)  


56.Li J, Shen Q, Zhang W, et al. Genomic organization and recombination analysis of a porcine sapovirus identified from a piglet with diarrhea in China[J]. Virology journal, 2017, 14(1): 57. (IF2.465)    


57.Guo Z, Long L, Ding S. Characterization of an L-Arabinose Isomerase from Bacillus velezensis and Its Application for L-Ribulose and L-Ribose Biosynthesis[J]. Applied Biochemistry and Biotechnology, 2020, 192(3): 935-951.(IF2.277)    


58.Liang W, Zhao C, Wang Y, et al. Antirestriction protein KlcAHS enhances carbapenem resistance[J]. Molecular Medicine Reports, 2020, 21(2): 903-908.(IF2.1)    


59.Zhu T, Zhao Y, Wu Y, et al. The Staphylococcus epidermidis gdpS regulates biofilm formation independently of its protein-coding function[J]. Microb Pathog, 2017,105: 264–271.(IF2.0)    


60.Ma, Y., et al., miR-1908 Overexpression Inhibits Proliferation, Changing Akt Activity and p53 Expression in Hypoxic NSCLC Cells[J]. Oncol Res, 2016. 24(1): p. 9-15.(IF1.74)    


61.Zhang M N, Tang Q Y, Li R M, et al. MicroRNA-141-3p/200a-3p target and may be involved in post-transcriptional repression of RNA decapping enzyme Dcp2 during renal development[J]. Bioscience, biotechnology, and biochemistry, 2018, 82(10): 1724-1732.(IF1.297) 

 

62.Li H H, Li J P, Liao X H. MKL-1 enhances luciferase activity of a reporter gene containing the miR-142 promoter in MDA-MB-231 cells[C]//BIBE 2019; The Third International Conference on Biological Information and Biomedical Engineering. VDE, 2019: 1-4.    


63.Cao G, Li P, Sun Q, et al. FHL3 Contributes to EMT and Chemotherapy Resistance Through Inhibiting Ubiquitination of Slug and Activating TGFβ/Smad-Independent Pathways in Gastric Cancer[J]. 2020.    


64. Li Tianxu,Zhai Xinyu,Wang Wenjie,Lin Yu,Xing Bin,Wang Jinchao,Wang Xiuyuan,Miao Runchun,Zhang Tingting,Wei Liangmeng. Regulation of MDA5-dependent anti-Tembusu virus innate immune responses by LGP2 in ducks[J]. Veterinary Microbiology,2021,263: (IF2.92)