Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/50 ChIP: 1/20
Western
Western blot analysis of Nrf2 in HepG2 lysates using Nrf2 antibody.
Immunohistochemistry
Immunohistochemistry analysis of paraffin-embedded Human kidney using Nrf2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Immunofluorescence
Immunofluorescence analysis of Nrf2 in Hela using Nrf2 antibody.
Western
Western blot analysis of Nrf2 in mouse liver lysates using Nrf2 antibody.
-15到-25度